Posts Tagged ‘Phosphodiesterase’
Forzest Treats Sexual Dysfunction in Men
Forzest is supposed to be the best treatment for the sexual dysfunction. Forzest was approved by the Food and Drug Administration in United States for the treatment of Impotence or sexual dysfunction. Forzest was approved by FDA in December 2003 after the clinical trials and checking the manufacturing standards.
Forzest is a reversible phosphodiesterase type 5 (PDE5) inhibitor approved for the treatment of sexual dysfunction. Forzest is a member of class PDE5 inhibitors that enhances erectile response to sexual stimulation by increasing blood flow to male reproductive system. Due to the relaxation of arteries and the smooth muscle of the corpus cavernosum the blood flow to the male reproductive organ is increased by Forzest during the sexual activity.
The recommended dosage of Forzest is 10 mg for the treatment of sexual dysfunction. The dose can be increased to 20 mg if necessary. Safe dosing of Forzest includes downward dosage adjustment to 5 mg in patients with moderate to severe renal insufficiency. In patients with mild to moderate hepatic dysfunction, the Forzest dose should not exceed 10 mg. Forzest is not recommended in patients with severe hepatic dysfunction.
Remember to take the dosage of Forzest 30 to 45 minutes before the sexual activity to see the maximum benefits. The main outcomes studied in the treatment of sexual dysfunction are achievement of an erection, successful intercourse, and overall satisfaction with sexual function. In the study evaluating Forzest in 5-, 10-, and 20-mg doses 321 men were assigned to a 10-mg regimen. In this group, 68 to 77 percent of men reported an erection suitable for insertion. However, slightly fewer men reported successful intercourse (51 to 70 percent). Satisfactory sexual experience was achieved by 56% men.
Concomitant use of nitrates with Forzest may also lead to severe contradictions. For life-threatening situations, nitrates may be considered if at least 48 hours have passed since the last dose of Forzest. Patients with cardiovascular diseases have been excluded from studies of Forzest because so little is known about its safety profile in this population. Thus, the patients with the cardiovascular diseases should contact the doctor before starting the dosage of Forzest.
The dose-related Forzest side effects are:
Headache and dyspepsia observed as most common side effects of Forzest. Back pain, beginning 12 to 24 hours after the dose and lasting for up to 48 hours, was reported in 5 to 6 percent of men, as compared with a rate of 3 percent in men receiving placebo.
Please consult your doctor before taking the dosage of Forzest because it will help you in saving your self from the adverse effects of the drug.
Vardenafil if Used With Precaution is a Safe Impotence Drug
About Levitra
With Vardenafil, an erection is produced via a complex chain of events, involving signals from the nervous system and the release of chemical messengers within the tissues of the penis. One of these chemical messengers is called cyclic GMP.
Cyclic GMP causes the blood vessels in the penis to widen by relaxing a thin layer of muscle found in the blood vessel walls. This allows more blood to enter the penis, which ultimately results in the penis becoming rigid and erect.
Cyclic GMP is normally broken down by another chemical in the body called phosphodiesterase type 5. Vardenafil works by preventing the action of phosphodiesterase type 5, thus stopping the breakdown of cyclic GMP. This means that the blood vessels remain dilated for longer period, thus improving blood flow to the penis and maintaining an erection.
As Vardenafil enhances the actions of the chemical messengers responsible for producing an erection, it will only work once these messengers are present. This means that sexual stimulation is required for it to produce and maintain an erection. The dose should be taken approximately 25 minutes to one hour before intended intercourse, and it may produce an erection in response to sexual stimulation up to five hours after taking the dose.
Ingredients of Levitra
Active ingredient in Levitra is Vardenafil. Whereas it’s inactive ingredients are:
Colloidal anhydrous silica
Crospovidone
Hypromellose
Iron oxide red (CI 77491 – E172)
Iron oxide yellow (CI 77492 – E172)
Macrogol 400
Magnesium stearate
Microcrystalline cellulose
Titanium dioxide (CI 77891 – E171)
Comes in the strength of
Your doctor or pharmacist is the best person to tell you how much and how often you should take Levitra. The doses come in 5mg, 10mg and 20mg strengths. Your doctor will determine the correct dose for you depending on your age, condition and response. Do not take more than one dose of Levitra a day.
Side Effects of Levitra
Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with Levitra. However, not everybody taking Levitra will experience the aforementioned side effects. Some of the commonly experienced side effects are:
Headache
Flushing
Dizziness
Inflammation of the lining of the nose
Indigestion
Nausea
Visual disturbances, like blurred vision, blue/green tinge to vision, watery eyes
Sleepiness
Increased heart rate
Palpitations
High or low blood pressure
Fainting
Shortness of breath
Nosebleeds
Photosensitivity
Pain or increased tension in the muscles
Prolonged or painful erections
Anxiety
Chest pain
The side effects listed above may not include all of the side effects reported by the drug’s manufacturer. For more information about any other possible risks associated with this medicine, please consult your doctor or pharmacist.
Availability of Levitra
Buying Levitra can be safe, convenient, and affordable and is available online, as well as at a pharmacy near you. Get a written prescription prior to buying Levitra online. It is best to buy the drug from a verified Internet Pharmacy Practice – a certified online pharmacy. Never buy a generic version of the drug as it could be unsafe and ineffective in treating erectile dysfunction (impotence).